The REVIVE LINE CREAM by Innete is a product designed to target fine lines and wrinkles. However, given the current data, there are no reviews available to provide specific insights on the best time to apply this product. Typically, line creams are applied in the morning and/or evening as part of your skincare routine. It is generally recommended to apply them after cleansing and toning, and before moisturizing. For the most accurate application instructions, it is advisable to refer to the product packaging or official brand guidelines.