PDRN in K-Beauty is known as a “skin-repair DNA ingredient,” used to support regeneration, calm irritation, and restore elasticity — all while strengthening the skin barrier. Originally used in medical wound care, this biotech ingredient is now formulated into everyday skincare so it can help repair, hydrate, and revitalize tired or stressed skin.
In this guide, we’ll break down what PDRN actually does, how to use it in your routine, and which top-reviewed products are worth trying.
1: What Is PDRN?
PDRN (Polydeoxyribonucleotide), often called the “skin repair DNA ingredient” in K-Beauty, is a DNA fragment extracted from salmon, first used in regenerative medicine. In skincare, it’s known to:
- Repair damaged skin faster
- Boost elasticity and firmness
- Deliver long-lasting hydration
Today, K-Beauty PDRN skincare has become one of the most talked-about repair categories for those struggling with irritation, sensitivity, or post-acne marks.
2: Hwahae User’s PDRN picks
1. Anua PDRN Hyaluronic Acid Capsule Serum
Anua PDRN Hyaluronic Acid Capsule Serum combines PDRN with hyaluronic acid capsules to deliver deep hydration while helping support skin repair and elasticity.
2. beplain Cica PDRN Skin Booster Serum
beplain Cica PDRN Skin Booster Serum soothes irritated skin with cica while the beplain Cica PDRN Skin Booster Serum works to strengthen the barrier and improve resilience.
3. DERMAFACTORY PDRN 4% Ampoule
DERMAFACTORY PDRN 4% Ampoule delivers a concentrated 4% PDRN formula that helps calm sensitivity and promote healthy-looking regeneration.
4. medicube PDRN Pink Cica Soothing Toner
medicube PDRN Pink Cica Soothing Toner comforts stressed skin with cica and PDRN, making the medicube PDRN Pink Cica Soothing Toner ideal for redness-prone or irritated skin.
5. VTCOSMETICS PDRN Cream 100
VT COSMETICS PDRN Cream 100 nourishes the skin barrier with PDRN while VT COSMETICS PDRN Cream 100 leaves skin soft, plump, and hydrated.
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3: What Hwahae Users Say About PDRN
Real Hwahae reviews show how PDRN performs in everyday K-Beauty products.
PDRN isn’t just a trendy ingredient — users consistently describe visible repair, better bounce, and lasting moisture, especially when using ampoules, serums, and creams with PDRN.
Hwahae Reviews
4: PDRN Pads & Masks for Daily Repair
These product formats make PDRN easy to fit into a daily routine, whether you need immediate calming or long-term skin resilience.
1. MEDIHEAL PDRN Lifting Pad
MEDIHEAL PDRN Lifting Pad delivers a firming and soothing boost with PDRN-infused toner pads that help improve elasticity while calming irritation.
2. medicube PDRN Pink Collagen Toning Gel Toner Pad
medicube PDRN Pink Collagen Toning Gel Toner Pad combines PDRN and collagen in a cooling gel pad to hydrate, tone, and comfort sensitive skin.
3. VTCOSMETICS PDRN Daily Mask
VT COSMETICS PDRN Daily Mask provides lightweight, daily-use hydration with PDRN to support skin recovery and resilience.
4. Genabelle PDRN Rejuvenating Mask
Genabelle PDRN Rejuvenating Mask delivers concentrated PDRN essence in a sheet mask format to help restore suppleness, bounce, and overall glow.
Editor’s Note
PDRN isn’t a miracle overnight fix — but it shines where consistency matters. With regular use, PDRN formulas can help your skin feel calmer, more elastic, and better supported when it’s irritated or stressed. Think of it as a long-term resilience builder, not just another trend.
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