PDRN skincare has evolved from a niche ampoule ingredient into a full routine across cleansers, mists, pads, serums, creams, and masks. New plant-based versions from seaweed and banana also broaden its appeal.
In this guide, we introduce new types of PDRN, and break down how these innovations fit into a modern, step-by-step PDRN routine
FAQ on PDRN
Q: How long does it take to see results with PDRN?
A: Most users notice better hydration quickly, while elasticity, smoothness, and recovery improve over 3–6 weeks with consistent use.
Q: Is PDRN safe for daily use?
A: Yes. Most K-beauty PDRN products are designed for daily use, especially in hydrating formats like toners, serums, creams, and masks. Always patch test first if you have reactive skin.
Q: What’s the difference between regular PDRN and plant-based PDRN?
A: Classic PDRN usually comes from salmon DNA. New plant-based versions like seaweed (GIM) and banana mimic similar hydration and repair benefits, with a lighter, eco-forward feel.
What Is PDRN Skincare? The Updated 2026 Overview
DRN (Polydeoxyribonucleotide) is one of the most studied DNA-derived skincare ingredients, known for improving elasticity, strengthening the skin barrier, and supporting visible recovery.
These benefits have made PDRN a core ingredient in modern K-beauty routines.
This updated 2026 guide builds on our original PDRN overview and expands into daily routines, plant-based innovations, and award-recognized formulas.
Build Your Daily 2026 PDRN Routine
Below is the full routine featuring top PDRN products available on Hwahae, including cleansers, mists, toner pads, serums, creams, and sleep masks.
PDRN Cleansers
Gentle formulas that begin hydration and barrier support from step one.
1. makep:rem — PDRN Pore Clay Cleansing Milk
makep:rem PDRN Pore Clay Cleansing Milk is soft, pH-balanced cleansing milk that removes impurities while supporting hydration.
2. Anua — PDRN Hyaluronic Acid Moisturizing Cleansing Foam
Anua PDRN Hyaluronic Acid Moisturizing Cleansing Foam is a cushiony foam that cleanses without stripping, ideal for dry or sensitized skin.
PDRN Mists
Lightweight delivery of hydration and fine elasticity support.
1. Anua — PDRN Hyaluronic Acid Hydrating Capsule Mist
Anua PDRN Hyaluronic Acid Hydrating Capsule Mist contains hyaluronic acid capsules that burst on skin for instant moisture and repair.
2. medicube — PDRN Pink Collagen Glow Jelly Mist Serum
medicube PDRN pink collagen glow jelly mist serum is a jelly-textured mist serum that boosts glow and elasticity.
PDRN Toner Pads
Daily texture-smoothing pads infused with PDRN and hydrating actives.
1. MEDIHEAL — PDRN LIFTING PAD
The PDRN Lifting Pad from MEDIHEAL is a nourishing PDRN toner pad that nourishes and hydrates skin- ideal for all skintypes.
PDRN Toners
Builds a hydrated, resilient base layer.
1. LABOREVE — PeachMicrobiome 78 PDRN Toner
PeachMicrobiome 78 PDRN Toner from LABOREVE is a lightweight regenerating toner infused with PDRN and peach micro-biome.
PDRN Serums & Ampoules
The heart of the PDRN toner serum cream routine, targeting elasticity and renewal.
1. medicube — PDRN Pink Collagen Bubble Serum
The PDRN Pink Collagen Bubble Serum from medicube contains collagen and high concentration PDRN, focused on firming and glow.
2. Haua — Hyaluronic PDRN Orb Serum
Hyaluronic PDRN Orb Serum from Haua is hyaluronic-acid-rich and boosts plumpness and barrier comfort.
PDRN Creams
Lock in moisture and support overnight renewal.
1. Re-Juvenil — Repair PDRNTX+ 1500 Cream
Re-juvenil Repair PDRNTX+ 1500 Cream is a concentrated repair cream ideal for elasticity support and dry skin.
Plant-Based PDRN Innovations — Seaweed(Gim) & Banana
Plant-based PDRN uses DNA fragments derived from seaweed and banana to offer a vegan alternative with similar repair and barrier-support benefits.
This shift marks the rise of plant-based DNA skincare, taking PDRN beyond salmon-derived formulas into gentler, eco-forward innovations that resonate with conscious consumers. With momentum building, we expect even stronger interest—and faster product innovation—as we move into 2026.
IsNtree — Gim PDRN
Uses a Korean seaweed-derived nucleotide complex to mimic traditional PDRN’s hydration and repair benefits while offering a cleaner, lighter feel.
1. GIM PDRN Boosting Glow Pad
IsNtree GIM PDRN Boosting Glow Pad are pre-soaked toner pads infused with GIM-derived PDRN to hydrate, smooth, and boost skin glow in one step.
2. GIM PDRN Deep Sleep Mask
IsNtree GIM PDRN Deep Sleep Mask is formulated with GIM-derived PDRN, hyaluronic acid, and vegan collagen, which delivers deep hydration while strengthening skin elasticity.
Celladix — Banana PDRN
Banana extract naturally contains DNA-like polymers that create a soft, moisture-retentive PDRN alternative.
1. Banana PDRN 2x Serum
Banana PDRN 2x Serum from Celladix is recommended for those with dry skin seeking for texture refinement and gentle everyday regeneration.
PDRN has evolved into a daily essential. Whether delivered through classic formulas or plant-based innovations like seaweed PDRN and banana PDRN, this ingredient shapes the future of slow-aging and barrier-first skincare.
🏆 PDRN Hwahae Awards Winners
Editor’s Note
PDRN has evolved into a daily essential. Whether delivered through classic formulas or plant-based innovations like seaweed PDRN and banana PDRN, this ingredient shapes the future of slow-aging and barrier-first skincare.
